Ivermectin is an antiparasitic medication widely known for its effectiveness in treating various parasitic infections. Initially developed for veterinary use, it has since gained approval for human use due to its efficacy in treating certain conditions such as onchocerciasis (river blindness), lymphatic filariasis, and strongyloidiasis. In recent years, it has been explored for its potential role in managing other types of infections, including scabies and head lice. This article will explore the recommended dosage of ivermectin for infection cure, the conditions it treats, and the importance of proper usage for effective treatment.
Understanding Ivermectin
Ivermectin 6 mg tablet dose works by binding to invertebrate muscle and nerve cells, causing paralysis and death of parasites. It is effective against a range of parasites, including nematodes (roundworms), arthropods (insects, ticks, and mites), and ectoparasites such as lice. However, it is not effective against all parasitic infections, and its use should be guided by a healthcare professional. It is available at online dosepharmacy in usa, uk and all over the world.
Common Conditions Treated by Ivermectin
Before discussing the recommended dosages of ivermectin, it is essential to understand the types of infections it can treat. These include:
- Onchocerciasis (River Blindness): Iverheal 12 contains Ivermectin, it is primarily used to treat this parasitic infection caused by Onchocerca volvulus. The disease can cause skin irritation, eye problems, and eventually blindness if left untreated.
- Strongyloidiasis: This infection, caused by the parasitic worm Strongyloides stercoralis, affects the intestines and can lead to gastrointestinal symptoms such as diarrhea, abdominal pain, and skin rash.
- Lymphatic Filariasis: Also known as elephantiasis, this condition is caused by parasitic worms that lead to severe swelling in the legs and other parts of the body. Ivermectin is used in combination with other medications to eliminate the parasites.
- Scabies: Scabies is a skin condition caused by the Sarcoptes scabiei mite, which burrows into the skin and causes intense itching and rash.
- Pediculosis (Head Lice): Ivermectin can also be used to treat head lice infestations.
- Other Uses: There has been interest in using ivermectin for the treatment of viral infections, including COVID-19. However, the use of ivermectin for viral infections remains a subject of research and is not universally recommended by health authorities.
Recommended Dosage of Ivermectin for Infection Cure
The appropriate dosage of ivermectin depends on the type of infection being treated, the patient’s weight, age, and overall health. It is essential to follow the guidance of a healthcare professional when taking ivermectin, as improper dosages can lead to reduced effectiveness or potential side effects.
1. Onchocerciasis (River Blindness)
The recommended dosage of ivermectin for onchocerciasis is:
- Dosage: 150 micrograms per kilogram (µg/kg) of body weight.
- Frequency: A single dose is typically given every 6 to 12 months. The reason for the periodic treatment is that ivermectin kills the microfilariae (immature worms) but does not affect adult worms. Repeated doses are required to continue reducing the microfilariae population over time.
2. Strongyloidiasis
The recommended dosage of ivermectin for strongyloidiasis is:
- Dosage: 200 micrograms per kilogram (µg/kg) of body weight.
- Frequency: A single dose is often sufficient, but some patients may require repeated doses, especially in cases of hyperinfection or disseminated strongyloidiasis. In cases of severe infection, follow-up treatment may be necessary based on clinical evaluation and stool examination to ensure complete eradication of the parasite.
3. Lymphatic Filariasis
Ivermectin is used as part of mass drug administration (MDA) programs for lymphatic filariasis elimination. The recommended dosage is:
- Dosage: 150 to 200 micrograms per kilogram (µg/kg) of body weight.
- Frequency: A single dose is typically given annually. In combination with albendazole or diethylcarbamazine (DEC), this helps to reduce the transmission of the parasite.
4. Scabies
The recommended dosage of ivermectin for scabies is:
- Dosage: 200 micrograms per kilogram (µg/kg) of body weight.
- Frequency: A single dose is usually effective, but in some cases, a second dose may be necessary after 1 to 2 weeks if the symptoms persist or if there is a severe infestation.
For crusted (Norwegian) scabies, which is a more severe form of the condition, repeated doses may be necessary along with the use of topical treatments such as permethrin cream.
5. Pediculosis (Head Lice)
Ivermectin is available as an oral or topical treatment for head lice. The recommended oral dosage is:
- Dosage: 200 micrograms per kilogram (µg/kg) of body weight.
- Frequency: A single dose is typically effective. However, some patients may require a second dose after 7 to 10 days if live lice are still present.
For topical ivermectin, a single application of 0.5% ivermectin lotion is usually sufficient. It is applied to dry hair and scalp, left for 10 minutes, and then rinsed off.
Important Considerations When Taking Ivermectin
While ivermectin is generally well-tolerated, there are important considerations to keep in mind to ensure safe and effective use:
- Medical Supervision: Always take ivermectin under the guidance of a healthcare professional. Self-medication can be dangerous, especially when the correct dosage is not known.
- Weight-Based Dosage: The dosage of ivermectin is typically calculated based on the patient’s weight. It is crucial to use the correct dose to avoid underdosing (which may not effectively clear the infection) or overdosing (which can lead to adverse effects).
- Pregnancy and Breastfeeding: Ivermectin is generally not recommended for use during pregnancy, particularly in the first trimester, unless the benefits outweigh the risks. It is also excreted in breast milk, so nursing mothers should consult their doctor before taking ivermectin.
- Side Effects: Common side effects of ivermectin include dizziness, nausea, diarrhea, fatigue, and rash. In rare cases, more severe reactions may occur, especially in patients with a high parasite load, due to the body’s reaction to dying parasites (e.g., the Mazzotti reaction in onchocerciasis). If severe side effects occur, seek medical attention.
- Resistance: Parasite resistance to ivermectin can occur with improper use or overuse. It is important to follow prescribed dosages and not take ivermectin unnecessarily to reduce the risk of developing resistance.
Conclusion
Ivermectin is a powerful antiparasitic medication with a range of uses for treating parasitic infections. The recommended dosage varies depending on the type of infection, patient weight, and other factors. It is essential to follow medical advice and take ivermectin as prescribed to ensure its effectiveness and minimize the risk of side effects. While ivermectin has garnered attention for potential off-label uses, such as for viral infections, its use for these conditions should be based on the latest medical guidelines and evidence. Always consult with a healthcare provider for proper diagnosis and treatment recommendations.
